松蘿酸.Usnic acid
一、Introduction:
Medicine material name : Pine Luo
English name: Usnea
Latin name:Lichen Usneae
The Chinese language pronounces:Songluo
Chinese nickname:
Live on on the female Luo, pine, the pine fall, day the Peng grass, snow breeze rattan, mountain hang a , dragon beard grass, money grass and close the male beard, day Peng grass, tree to hang, fly for a day, centipede, pine hair, sea breeze rattan, stone silk thread, fly mountain wings, the fairy head to deliver, gold silk rattan, cloud and mist grass, old gentleman beard, beard grass, tea beard, lead a mountain dragon, stone beard.
Come to source:
Belong to the plant stanza pine Luo Usnea diffracta Vain or long pine Luo Usnea longissima Ach for the pine Luo section pine Luo.Of dry lichen body.
Sex flavor:The flavor is sweet, sex is even
The Ji is a characteristic at first:
1. The stanza pine Luo-again:Wreath Lie Luo pine, break a caulis Luo pine.The lichen body form, hang to hang a type, long 15-50 cms.The thin celadon goes to thin and yellow green.The body Ji department diameter about 3 mms, main thick 3-4 mms, time the that gets a cent is tidy or not tidy to return to two more fork pay the cylinder form for cent, few bitter ends are slightly flat even or have sharp angle.The branch and trunk has the wreath form Lie Xi, as vertebrate form.
Was born in tree trunk, on the branch and trunk.Distribute in the northeast and the mountain west, Inner Mongolia, Xia west, sweet Su, Anhui, Zhejiang, river's west, Fukien, Taiwanese etc. ground.
2. Long pine Luo-again:Grow a Luo pine.The lichen body form, long about 20-40 cms, sometimes the long 1 m is above, the silk form hangs to hang, the main and the entry-level cent are very short, second class separately is soft and thin long, it top airtight get a perpendicular and small, have no x-rated cent.Surface celadon, the grass green color, old ash grass yellow.The main has the skin layer, second class cent lack of a skin layer.Get on the tree trunk and the tree branch.Distribute in Heilongjiang, Jilin, Inner Mongolia, mountain west, sweet Su, Zhejiang, Fukien, Taiwan, Szechwan, Yunnan, Tibet etc. ground.
Main composition:
1. Stanza pine Luo:Of the lichen silk the form body contain Ba the Er Ba's lichen sour(the Barbatic acid , the pine Luo is sour(the Usnic acid , ground the Fu lichen is sour(the Diffractaic acid).
2. Long pine Luo:Of the lichen silk the form body contain Ba the Er Ba's lichen sour, the pine Luo is sour, ground the Fu lichen is sour and pull a horse sour(the Ramalic acid), the lichen gather sugar(Lichenin), the long pine Luo many sugar, flat B ester(the Ethyl everninate) with sour dress.
Medicine material form:
Present a yellow green or pale green color for the small segment, have of it is thus clear that divide into.The surface has wreath form crack.Slice as hypha, the quality is pliant and tough, having flexibility, can make longer.Long pine Luo two sides have the thin but short side, having no flexibility.
Sex flavor returns through:Sweet, even.Return liver, lung through.
The function lord cures:Dispeling the breeze limbers up, the pure heat counteracts poison, stopping coughing to turn phlegm.Be used for the rheumatism joint ache, lumbago, hot phlegm disadvantage, external injury issue of blood;Rheumatism arthritis, chronic bronchitis.
Does the lord cure the cold and hot disease, the headache head Chuang, Luo Tubercle, cough, suffer from insomnia, the cold heat, guest in the gonorrhea, scrotum inflammation, breeze hot pneumonia, chronic bronchitis and chest hot phlegm Xian, cough many phlegm.Can also cure red malaria of eyes, can make emetic, diuretic.
Cure with the lord outside after operation the wound infection, the wound knife wound infection, maturation middle-ear infection, Chuang Jie Ying lump, lymphoid tubercle, mastitis and burn burn, the cervix debauched, the vagina infusoria infection, external injury bleed etc..
二、The pine Luo sour chemistry type:
Chemistry composition
Grow the pine Luo and break the caulis pine Luo to all contain Ba the Er Ba's lichen sour, the pine Luo is sour, ground the Fu lichen is sour.The long pine Luo contains to pull a horse still sour, the lichen gather sugar.Break the caulis pine Luo to contain to differ from Ba the Er Ba's lichen still sour of another a kind of sour, the melting point is 189-190 ℃ .Also contain the carbon water to turn a thing in addition.
Usnic acid |
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Systematic name |
2,6-Diacetyl-7,9-dihydroxy-8,9b-dimethyl-1,3(2H,9bh)
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Other names |
usneine, usninic acidusneine,usninic |
Chemical formula |
C 18 H 16 O 7 |
Density |
x.xxx g/cm 3x.xxx |
Melting point |
204°C204℃ |
Boiling point |
xx.x °Cxx.x℃ |
CAS number |
125-46-2125-46-2 |
SMILES |
CC1=C(C(=C2C(=C1O)C3(C(=CC(=O)C(C3=O)C(=O)C)O2)C)C(=O)C)O |
三、The pine Luo sour pharmacology function:
Anti-virus function
The pine Luo belongs to wait for many lichens to all have anti-virus material, among them, the pine Luo is sour of the anti-virus function is particularly outstanding.Its nti-virus table is main for the surname of Ge Lan male germ and tubercle rod bacteria.The pine Luo is sour to the pneumonias ball germs and dissolve guts streptococci, diphtheria rod bacteria, the tubercle rod bacteriases to all have to suppress the germ function very strongly in the tube, is suppressing the germ density 1-5 tiny tiny gram/milliliters can repress the growth of the germ completely.Repress golden color staphylococcus a more above-mentioned germ slightly weak, but strong in to the function of the Ge Lan surname feminine gender germ.The right Xuan has no big difference with the anti-virus function of the left Xuan type.But also have report to the whooping cough rod bacteria, withered grass rod bacteria, the pneumonia rod bacteria of the Ge Lan surname feminine gender is go to escherichia coliform, transform a rod bacteria effectively, then is invalid to the dysentery rod bacteria, the typhoid rod bacteria.Experiment to win outside body, the pine Luo is sour type the tubercle rod bacteria repressed a function obviously to the person, 20-50 tiny gram/milliliters canned acquire to repress completely, the serum can reduce its effect slightly.Experiment in the body in(to the treatment of the experiment tubercle of the guinea pig), think generally take orally or the belly cavity inject to have better curative effect, can limit the development of the tubercle pathological changes;Also someone reports the list uses the pine Luo sour, have no influence to the guinea pig experiment tubercle, but can strengthen the function of the chain fungi vegetable.
In the tube, it and the chain fungi the plain or different smoke also has a light degree to be in conjunction with a function.Take orally gram pine Luo sour Na salt or Evosin(a kind of contain the pine Luo sour and the Suo type oak Xian sour product)s grams everyday to the person's lung, the bowel tubercle, can make some condition of illnesses of the tuberculosis,such as a cough, loss of appetite, , have fever or the bowel tubercle diarrhea etc., acquire an amendment, even make the mirror check of the tubercle germ turn Yin, but observe still not enough perfect, can't descend end conclusion.The amendment of the above-mentioned condition of illness, seem to be not medicine to the direct function of the tubercle germ, because take orally after, could not attain level of suppressing the germ density in the blood.Someone thinks its tuberculosis to person has no obvious curative effect.The home uses sour treatment tuberculosis of the pine Luo, having ever observed to have certain curative effect.
To the germ toxin and bite the influence of the germ body
been sour to mix with the tetanus infection toxin or the diphtheria toxin by pine Luos or inject in 10 minutes after the toxin inject, can make the small rat bear to be subjected to 2 times toxins to cause death quantity.2 hours after inoculating the diphtheria rod bacteria to the guinea pig, the subcutaneous injection pine Luo is sour 2 milligrams/kilogramses, or in advance two hybrid development again inoculate in the guinea pig, all have an obvious protection function.The small rat experiment tetanus infection, the pine Luo is sour to unite applied result with penicillin best.Use the paper disc a method certificate, the d-pine Luo the sour have already resisted a function of biting the germ body.
To the function of other cause bodies.
The pine Luo is sour to have already repressed a function as well to the protozoas, the vagina infusorias.The schistosome, the liver slice that takes orally sour Na of the pine Luo sheep absorbs an insect to all have injury and kill to put out a function, muscle's injecting can meet with better result;To the rabbit schistosome, because its toxicity compares greatly, and uses a sour aniline of its derivatives-pine Luo, taking orally milligrams/kilograms/days, connecting to take for 9 days, also acquiring good result.
Other functions
Big rat cut off to parts of livers, feed on the pine Luo sour have a function of promoting the liver rebirth.Can reduce to leave horizontal Ge of big rat of body to the exploitation and its sugar dollar content of the glucose.Anaesthetizing the cat vein injects sour Na of the pine Luo 30 milligrams/kilograms, can make the blood sugar go up.The d-pine Luo is sour and can be obvious to repress the abruption of the starfish fertilizied egg and phosphoric take, and to oxygen consume several then have no influence.It can also repress the activity that the grain of the big rat stomach water lump cell α -glycerin phosphoric acid inside the line body is lately the four Shis revivification.The d-pine Luo is sour to leave body guinea pig, the frog heart to all have already repressed a function;Infuse to flow towards leaving the body rabbit ear and the legs of Chan Chu.
四、The pine Luo sour hairdressing effect:
Have stronger suppress the germ and the anti- inflammation effect, can cure the wound skin, and, can resist the function that the corn of[with] the skin excessiveness turns cell, usually be used for to the product of making the medicine cream.
